The consequences for greed and exploitation are absolute. Those who use their power to strip others of their land and homes ultimately lose their own place in the future of the nation. This direct connection between the crime of land theft and the resulting penalty is aimed squarely at the corrupt families who stole from the vulnerable [מצודת דוד, אבן עזרא]. However, some suggest the warning is directed personally at a false prophet whose actions led to the ruin of the nation's inheritance [רד״ק].
To fully grasp the severity of this loss, one must understand how land was traditionally divided among heirs. First, a general region for a tribe or family was selected by lottery. Once the region was established, the land was physically measured out into individual plots using a standard measuring rope [מלבי״ם, מצודת דוד, רש״י, מצודת ציון]. The primary approach among commentators is that the punishment strikes directly at the legacy of the oppressor. His family line will be completely cut off, leaving no child or descendant eligible to receive a measured plot of land, effectively erasing his memory.
Conversely, another perspective focuses on the thieves themselves rather than their descendants. In this scenario, an invading enemy will destroy the homes of the wealthy and force them into exile. The poorest citizens will be left behind to work the fields and vineyards. As a result, the stolen lands will naturally revert to their original, rightful owners, while the wealthy thieves will be left with absolutely nothing [מלבי״ם].
The ultimate realization of this punishment will occur during the future return from exile. Commentators agree that when the Israelites eventually return to their land and divide it once again, the descendants of these sinners will be entirely excluded from the distribution. On a broader historical scale, this serves as a judgment against the entire northern Kingdom of Israel. Unlike the tribe of Judah, the Ten Tribes will not return during the era of the Second Temple and will have no share in God's inheritance at that time [אברבנאל]. Furthermore, there is a view that these words of doom may not only be a prophetic warning. They might actually capture the ongoing, bitter curse spoken by the ruined victims, directed at the very people who robbed them [אברבנאל].