The tragedy of sin fundamentally shatters the natural cycle of life, turning the immense effort of raising a family into profound loss and spiritual abandonment. All the pain, care, and dedication parents invest in pregnancy and childbirth ultimately come to nothing [רש״י]. Even if the children manage to survive the fragile stages of birth and infancy, they face an untimely death [מצודת ציון, ביאור שטיינזלץ]. The primary approach among commentators is that these children will perish in their youth, dying before they can reach full adulthood and be recognized as grown individuals [רד״ק, מצודת דוד]. Offering a starkly different perspective, another viewpoint suggests a deeper moral tragedy: the children lose their human status entirely. Because they are born into a culture of sin, assimilation, and immorality, they are never considered truly human to begin with [מלבי״ם].
The disaster does not end with the loss of the next generation; rather, the tragedy intensifies as the focus shifts directly to the parents themselves [רש״י, מלבי״ם]. The ultimate consequence is a complete withdrawal of divine protection. Not only do the parents suffer the grief of losing their children, but ruin and hardship will plague everything they do. Because of their evil actions, God will hide His face, remove His guiding providence, and completely turn away from them, leaving them entirely exposed to misfortune [רד״ק, מצודת דוד, ביאור שטיינזלץ].