יחזקאל, פרק ל׳, פסוק י״ד

A systematic collapse of Egypt's major centers is foretold, designed to completely shatter the nation's false sense of security in its fortified cities [אברבנאל]. The path of ruin is not random. Instead, it follows a deliberate geographical route, sweeping from Upper Egypt down to Lower Egypt [מלבי״ם].

The devastation begins with desolation striking Pathros, a region situated in Upper Egypt [מלבי״ם]. Following this, destruction moves to Zoan, a city that once served as the capital of the Egyptian empire [ביאור שטיינזלץ]. The fire that consumes this capital might be literal flames falling from the sky, or it could serve as a symbol for a massive slaughter carried out by Nebuchadnezzar [אברבנאל].

Finally, God will execute His judgments upon No, the great metropolis also known as No Amon [ביאור שטיינזלץ]. There is a broad agreement among commentators, relying on the translation of Yonatan, that this city is actually Alexandria [רש״י, רד״ק, מצודת ציון, אברבנאל], located in the lower region of Egypt [מלבי״ם].