A devastating judgment targets the most vital centers of population and defense in ancient Egypt. God directs His wrath toward the two largest and most important cities in the nation at that time, Sin and No [ביאור שטיינזלץ]. The city of Sin stands as a powerful stronghold. It is a highly fortified location that serves as a primary fortress and a safe haven [מצודת דוד, מצודת ציון, ביאור שטיינזלץ]. Meanwhile, the city of No is defined by its massive population, filled with multitudes of residents [מצודת דוד].
A tragic sequence of events links these two great cities together. As disaster strikes, the massive crowds living in No will attempt to escape by fleeing to the nearby fortress city of Sin, hoping to find safety within its strong walls. Because they gather there, God will pour out His anger directly onto Sin. Ultimately, the very people of No who ran to the fortress for protection will be entirely destroyed inside the place they thought would keep them safe [מלבי״ם].