A deep sense of absolute helplessness defines a person who is trapped between an unstoppable force and a justice system that cannot be reached. In his suffering, Job finds himself in exactly this position against God, caught between the Creator's overwhelming power and the impossibility of receiving a fair trial.
Job realizes that if this is a matter of physical strength and conflict, or an attempt to escape God by force, the struggle is entirely futile. God is vastly powerful, and there is simply no way to stand against Him [רש״י, רמב״ן, ביאור שטיינזלץ]. If human suffering is driven solely by God's absolute might rather than justice, then He can do whatever He pleases. No one can use force to compel Him to shift His behavior from harshness to mercy [מצודת דוד, מלבי״ם]. Taking a unique perspective, one approach suggests that God's immense power is already tangibly proven right before our eyes. The very fact that God manages to keep Job alive through such severe agony, leaving him in an unnatural state of the living dead, is a clear display of His might [אלשיך].
Turning from physical power to the possibility of law and justice, the situation remains just as hopeless. The concept of justice requires setting an agreed time or issuing an official summons to a court [מצודת ציון, אבן עזרא, מלבי״ם]. Job argues that even if his suffering is a legal judgment for his sins, as his friends claim, he has no path forward. There is no higher judge or supreme authority who could possibly set a court date, summon both parties, and determine who is right [רמב״ן, מצודת דוד, ביאור שטיינזלץ]. Furthermore, even if such a trial could somehow take place, there is no one who could testify in Job's favor, uphold his claims, and ensure he is found innocent against God [רש״י, מלבי״ם, תקות אנוש]. However, another viewpoint suggests that Job actually deeply desires to stand trial with God to clarify his misdeeds. Yet, because he is too ashamed to summon God himself, he searches for a mediator who could call them both to court in his place, thereby removing his shame [אלשיך].