God's infinite power might seem like a reason for Him to distance Himself from humanity, but the exact opposite is true. True greatness results in deep, compassionate involvement in human life. Unlike the assumption that a vast gap in status causes the Creator to ignore His creations, His absolute perfection guarantees His personal care. He encompasses all perfections [מלבי״ם] and is infinitely great in wisdom, mercy, and providence [רש״י, רלב״ג]. Because of this profound greatness, God does not reject or destroy human beings without cause [אבן עזרא, ביאור שטיינזלץ]. The primary approach among commentators is that even though God is infinitely high and powerful, and humanity is fleeting, He does not look down on the poor and lowly. Instead, He watches over the work of His hands with deep compassion. Furthermore, when many people gather together to pray and ask for mercy, God never turns away their united plea [מנחת שי].
A fascinating discussion arises regarding who exactly possesses a mighty strength of heart. Some commentators understand this as a description of God Himself. In this view, God is endowed with the strength and wisdom to contain multitudes [ביאור שטיינזלץ] and to prepare the human mind to grasp true wisdom [רלב״ג]. His immense power is actually demonstrated through His patience. He shows great restraint toward sinners, giving them time to repent and return to Him [תקות אנוש]. At the same time, this divine strength and wisdom allow Him to capture the proud and bring justice to the wicked [רש״י, רמב״ן].
Conversely, other scholars believe this mighty strength describes the human being whom God refuses to reject. God values and stays close to a person who maintains a strong, firm heart, standing resilient against life's trials and negative urges without straying from the righteous path [מצודת דוד, מלבי״ם]. Taking a different angle on the human heart, another perspective notes that God recognizes just how powerful and overwhelming the human urge to do wrong can be. Because He understands the immense struggle required to conquer these inner forces, God does not reject a sinner who ultimately repents, recognizing the profound difficulty they faced in their initial battle [אלשיך].