The exiles of Judah who fled to Egypt face a grim and inescapable fate of absolute destruction. Unlike the exiles taken to Babylon, who received a promise that they would eventually return to their land, those who sought refuge in Egypt have no hope of ever seeing their homeland again [ביאור שטיינזלץ]. The prophecy speaks directly to the people who never planned to settle in Egypt permanently. They only intended to live there temporarily, holding onto a clear plan to go back [מלבי״ם]. These individuals constantly raise their hopes, deeply longing, expecting, and promising themselves that they will soon return to the land of Judah [מצודת ציון, ביאור שטיינזלץ].
Despite their deep yearning, the decree against them is final. No survivor or remnant will be left to experience rescue [מצודת דוד, מצודת ציון]. Even the individuals who did not actively fight against Nebuchadnezzar are destined to meet their end through famine and plague [מלבי״ם].
Nevertheless, there is a slight exception to this absolute destruction, as a tiny fraction of people will manage to return. The primary approach among commentators is that this refers to a very small number of individuals who will somehow manage to escape the enemy sword and the massive devastation that will strike Egypt [מצודת דוד, ביאור שטיינזלץ], becoming the few rescued fugitives [מצודת ציון]. Alternatively, this small group of survivors does not refer to the general population at all. Instead, it points to specific individuals, exclusively identifying the prophet Jeremiah and Baruch son of Neriah. In this view, they are the only ones who returned to the land of Judah after Nebuchadnezzar conquered Egypt and exiled them from there [רש״י].