A person trapped in deep, ongoing distress often reaches a point of total physical and mental exhaustion, where every effort to find relief seems to fail. The imagery paints a picture of someone drowning in the sea. They first cry out to the people around them for help until their throat is completely dry. When no human answers, they turn their gaze upward, waiting for divine rescue until all their strength is gone [רד״ק, מלבי״ם, מאירי].
The sufferer is worn out from the sheer volume of their shouts for rescue, overwhelmed by the intense pressure of the situation [מצודת דוד, שטיינזלץ]. This desperate calling leaves the throat stripped of all moisture because the cries go unanswered. Alongside this loss of voice comes a fading of vision and hope. The eyes tire from a prolonged wait, constantly searching for an escape and looking for a salvation that is delayed [רש״י, אבן עזרא, מצודת דוד, שטיינזלץ].
Beyond personal pain, this deep exhaustion represents the long periods of exile and the collective suffering of the Israelites as they wait for God to save them [רד״ק, מאירי]. Some view this specifically through the lens of the Greek exile and its harsh decrees. During that time, the Greeks attempted to destroy the people's faith, demanding they declare they had no connection to the God of Israel. In an act of defiance and complete devotion, much like the sacrifice of Hannah and her seven sons, the Israelites placed their trust entirely in God. Their declaration of hope in Him served as a direct challenge to those who tried to sever that bond [אלשיך].
A completely different approach shifts the focus from external suffering to internal spiritual repair and repentance. In this view, the specific physical struggles represent personal flaws that require correction. The exhaustion from calling out points to mistakes made through speech. The dry throat serves as a correction for eating forbidden foods. Finally, the tired eyes reflect deep sorrow for wrongdoings committed in thought [חומת אנך].